Publications (Newest First; # denotes co-corresponding authors; * denotes equal contributions):

• Boswell, C.W., Hoppe, C., Sherrard, A., Miao, L., Kojima, M.L., Martino, P., Zhao, N., Stasevich, T.J., Nicoli, S., and Giraldez, A.J. (2025). Genetically encoded affinity reagents are a toolkit for visualizing and manipulating endogenous protein function in vivo. Nat Commun 16, 5503.
• Youlten, S.E.*, Miao, L.*, Hoppe, C., Boswell, C.W., Musaev, D., Abdelmessih, M., Krishnaswamy, S., Tornini, V.A., and Giraldez, A.J. (2024). Novel cell states arise in embryonic cells devoid of key reprogramming factors. bioRxiv, 2024.2005.2013.593729.
• Pownall, M.E.#, Miao, L.#, Vejnar, C.E., M'Saad, O., Sherrard, A., Frederick, M.A., Benitez, M.D.J., Boswell, C.W., Zaret, K.S., Bewersdorf, J., and Giraldez, A.J.# (2023). Chromatin expansion microscopy reveals nanoscale organization of transcription and chromatin. Science 381, 92-100.
• Tornini, V.A., Miao, L.*, Lee, H.J.*, Gerson, T., Dube, S.E., Schmidt, V., Kroll, F., Tang, Y., Du, K., Kuchroo, M., et al. (2023). linc-mipep and linc-wrb encode micropeptides that regulate chromatin accessibility in vertebrate-specific neural cells. Elife 12.
• Boswell, C.W., Hoppe, C., Sherrard, A., Miao, L., Kojima, M.L., Krishna, S., Musaev, D., Zhao, N., Stasevich, T.J., and Giraldez, A.J. (2023). Genetically encoded affinity reagents (GEARs): A toolkit for visualizing and manipulating endogenous protein function in vivo. bioRxiv, 2023.2011.2015.567075.
• Tornini, V.A., Lee, H.-J., Miao, L., Tang, Y., Dube, S.E., Gerson, T., Schmidt, V.J., Du, K., Kuchroo, M., Kroll, F., et al. (2022). linc-mipep and linc-wrb encode micropeptides that regulate chromatin accessibility in vertebrate-specific neural cells. bioRxiv, 2022.2007.2021.501032.
• Miao, L.*#, Tang, Y*., Bonneau, A.R., Chan, S.H., Kojima, M.L., Pownall, M.E., Vejnar, C.E., Gao, F., Krishnaswamy, S., Hendry, C.E., and Giraldez, A.J. # (2022). The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation. Mol Cell 82, 986-1002 e1009.
• Miao, L.*, Tang, Y.*, Bonneau, A.R., Chan, S.H., Kojima, M.L., Pownall, M.E., Vejnar, C.E., and Giraldez, A.J. (2020). Synergistic activity of Nanog, Pou5f3, and Sox19b establishes chromatin accessibility and developmental competence in a context-dependent manner. bioRxiv, 2020.2009.2001.278796.
• Sun, Y., Zhang, B., Luo, L., Shi, D.L., Wang, H., Cui, Z., Huang, H., Cao, Y., Shu, X., Zhang, W., et al. (2019). Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome Res 30, 118-126.
• Chan, S. H., Tang, Y., Miao, L., Darwich-Codore, H., Vejnar, C. E., Beaudoin, J. D., Musaev, D., Fernandez, J. P., Benitez, M., Bazzini, A. A., Moreno-Mateos, M. A., & Giraldez, A. J. (2019). Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation. Developmental Cell, 49(6), 867–881.e8.
• Chan, S.H., Tang, Y., Miao, L., Darwich-Codore, H., Vejnar, C.E., Beaudoin, J.-D., Musaev, D., Fernandez, J.P., Moreno-Mateos, M.A., and Giraldez, A.J. (2018). Brd4 and P300 regulate zygotic genome activation through histone acetylation. bioRxiv, 369231.
• Fernandez, J.P., Moreno-Mateos, M.A., Gohr, A., Miao, L., Chan, S.H., Irimia, M., and Giraldez, A.J. (2018). RES complex is associated with intron definition and required for zebrafish early embryogenesis. PLoS genetics 14, e1007473.
• Zhu, D., Gong, X., Miao, L., Fang, J., & Zhang, J. (2017). Efficient Induction of Syncytiotrophoblast Layer II Cells from Trophoblast Stem Cells by Canonical Wnt Signaling Activation. Stem Cell Reports 9(6), 2034–2049.
• Miao, L., Yuan, Y., Cheng, F., Fang, J., Zhou, F., Ma, W., Jiang, Y., Huang, X., Wang, Y., Shan, L., Chen, D., Zhang, J. (2017). Translation repression by maternal RNA binding protein Zar1 is essential for early oogenesis in zebrafish. Development (Cambridge, England) 144, 128-138.
• Cheng, F., Miao, L., Wu, Q., Gong, X., Xiong, J., and Zhang, J. (2016). Vinculin b deficiency causes epicardial hyperplasia and coronary vessel disorganization in zebrafish. Development (Cambridge, England) 143, 3522-3531.
• Fang, J., Wang, H., Miao, L., Kuang, X., Ma, W., Wang, C., Zhang, J., and Xia, G. (2016). Involvement of Protein Acyltransferase ZDHHC3 in Maintaining Oocyte Meiotic Arrest in Xenopus laevis. Biology of Reproduction.
• Wang, H, Fang, J, Kuang, X., Miao, L., Wang, C., Xia, G., King, M.L., and Zhang, J. (2012). Activity of long-chain acyl-CoA synthetase is required for maintaining meiotic arrest in Xenopus laevis. Biology of Reproduction.